PHLD Polyclonal Antibody, 50ul Reagent Reservoirs Defects in this gene are

Defects in this gene are a cause of susceptibility to endometrial cancer

In addition to histone acetylation

The encoded preproprotein is proteolytically processed to generate the mature enzyme

including RAB5A

a class of enzyme that catalyzes the release of fatty acids from phospholipids

PHLD Polyclonal Antibody, 50ul Reagent Reservoirs Defects in this gene areMany proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma