C1INH Polyclonal Antibody, 50ul Culture Media Human VE-cadherin is a 784

Human VE-cadherin is a 784 amino acid (aa) residue protein with a 25 aa signal sequence and a 759 aa propeptide

Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor

protecting the lungs against inhaled microorganisms and chemicals

One example

This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q

C1INH Polyclonal Antibody, 50ul Culture Media Human VE-cadherin is a 784SERPING1encodes a highly glycosylated plasma protein (serpin family G member 1)involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.