CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette Alpha-1B-glycoprotein encoded by A1BG is

Alpha-1B-glycoprotein encoded by A1BG is a plasma glycoprotein of unknown function

and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion

This gene is expressed in both normal and tumor cells

Acts as a costimulatory signal for T-cell proliferation and cytokine secretion

It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues

CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette Alpha-1B-glycoprotein encoded by A1BG isCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.