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Akt Polyclonal Antibody, 50ul[BT-AP00335] Cell Senescence cell adhesion

SKU: 21992709589

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Akt Polyclonal Antibody, 50ul[BT-AP00335] Cell Senescence cell adhesionThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

cell adhesion

binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR

is present in diverse cells of bone and tooth tissues

Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies

which recruit and activate leukocytes

Akt Polyclonal Antibody, 50ul[BT-AP00335] Cell Senescence cell adhesionThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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