ASK1(Phospho Thr838) Rabbit Polyclonal Antibody, 50ul RNA Synthesis This kinase has been shown

This kinase has been shown to be involved in many different cellular functions

Leukocyte immunoglobulin-like receptor subfamily A member 5 encoded by LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family

Mutations in this gene have been associated with arterial tortuosity syndrome

mevalonic acid biosynthesis

Interstitial collagenase in this family are involved in the breakdown of extracellular matrix in normal physiological processes

ASK1(Phospho Thr838) Rabbit Polyclonal Antibody, 50ul RNA Synthesis This kinase has been shownCatalytic activity: ATP + a protein = ADP + a phosphoprotein. cofactor: Magnesium. enzyme regulation: Contains an N terminal autoinhibitory domain. Activated by phosphorylation at Thr 838 inhibited by phosphorylation at Ser 966 and Ser 1033. Binds to and stabilizes MAP3K6 and is activated by MAP3K6 by phosphorylation on Thr 838. Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6 which in turn