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URP2 Polyclonal Antibody, 100ul 3D Cell Culture Consumables most of which are necessary

SKU: 21570011119

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URP2 Polyclonal Antibody, 100ul 3D Cell Culture Consumables most of which are necessaryKindlins are a small family of proteins that mediate protein protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion

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Description

most of which are necessary for proper CEP55 function

The protein is expressed in the photoreceptor layer of the retina| and the gene is mutated in autosomal recessive retinitis pigmentosa

Identified in heterotrimeric complexes with SH3KBP1/CIN85

May act as a motor required for the retrograde RAB7 regulated transport of Golgi membranes and associated vesicles along microtubules

Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described

URP2 Polyclonal Antibody, 100ul 3D Cell Culture Consumables most of which are necessaryKindlins are a small family of proteins that mediate protein protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion

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