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ABCB8 Polyclonal Antibody, 100ul Dry Bath Multiple alternatively spliced transcript variants

SKU: 21538390642

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ABCB8 Polyclonal Antibody, 100ul Dry Bath Multiple alternatively spliced transcript variantsThis nuclear gene encodes a multi pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.

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Description

Multiple alternatively spliced transcript variants that encode different proteins have been described

It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina| and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle

The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule| and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression

This gene encodes an enzyme that belongs to the methyltransferase family

kidney and liver

ABCB8 Polyclonal Antibody, 100ul Dry Bath Multiple alternatively spliced transcript variantsThis nuclear gene encodes a multi pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.

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