MYCN Polyclonal Antibody, 50ul Molecular Sciences NOLC1 (Nucleolar And Coiled-Body Phosphoprotein

NOLC1 (Nucleolar And Coiled-Body Phosphoprotein 1) is a Protein Coding gene

Mutations in this gene are associated with X-linked mental retardation

This gene encodes a member of the TFB4 family

UBTF encodes a member of the HMG-box DNA-binding protein family

including regulation of iron homeostasis

MYCN Polyclonal Antibody, 50ul Molecular Sciences NOLC1 (Nucleolar And Coiled-Body PhosphoproteinThis gene is a member of the MYC family and encodes a protein with a basic helix loop helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.