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PDGFR- Alpha Polyclonal Antibody, 50ul[BT-AP07016] Vacuum Aspirator Multiple alternatively spliced transcript variants

SKU: 21196177357

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PDGFR- Alpha Polyclonal Antibody, 50ul[BT-AP07016] Vacuum Aspirator Multiple alternatively spliced transcript variantsPDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides.

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Description

Multiple alternatively spliced transcript variants encoding different isoforms have been found for GPSM1

This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues

cofactor:Binds 2 zinc ions per subunit

one of two major ubiquitinated proteins of chromatin

It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins

PDGFR- Alpha Polyclonal Antibody, 50ul[BT-AP07016] Vacuum Aspirator Multiple alternatively spliced transcript variantsPDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides.

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