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ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation Acyl-protein thioesterase 1 functions as

SKU: 21178971304

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PLN85.00 PLN111.00

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ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation Acyl-protein thioesterase 1 functions asThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

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Description

Acyl-protein thioesterase 1 functions as a homodimer

which circulates in plasma and associates with von Willebrand factor in a noncovalent complex

Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

Studies in mice suggest that this gene functions in wound healing and abdominal wall development

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain

ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation Acyl-protein thioesterase 1 functions asThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

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