Rb (Acetyl-K873/K874) Polyclonal Antibody, 50ul Pipette Filler Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain

This gene encodes a member of the PSCD family of proteins| which have an N-terminal coiled-coil motif| a central Sec7 domain| and a C-terminal pleckstrin homology (PH) domain

The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes

the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing

Rb (Acetyl-K873/K874) Polyclonal Antibody, 50ul Pipette Filler Gene Ontology (GO) annotations relatedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.