LPAR6 Polyclonal Antibody, 50ul Monoclonal Antibodies The SAM and HD domain

The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses

and organization of organelles

Transcript variants encoding different isoforms have been described for this gene

cts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function

A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis

LPAR6 Polyclonal Antibody, 50ul Monoclonal Antibodies The SAM and HD domainThe protein encoded by this gene belongs to the family of G protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants.