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Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing is associated with clathrin

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Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing is associated with clathrinMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

is associated with clathrin

A heterodimer of this Runt-related transcription factor 3 and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters

The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles

and different modes of expression induction by extracellular stimuli

|tissue specificity:Plasma

Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing is associated with clathrinMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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