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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression SCF(FBXO33) directs ubiquitination of YBX1

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression SCF(FBXO33) directs ubiquitination of YBX1This gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

SCF(FBXO33) directs ubiquitination of YBX1 (By similarity)

The larger transcript is approximately 13

Several alternatively spliced transcript variants have been described for this gene

This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins

These optimized lentiviruses deliver efficient

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 100ul Mammalian Expression SCF(FBXO33) directs ubiquitination of YBX1This gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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