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PAK gamma(Phospho Ser197) Polyclonal Antibody, 20ul Biomatrix subunit:Component of multiple ECS (Elongin

SKU: 19629407364

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PAK gamma(Phospho Ser197) Polyclonal Antibody, 20ul Biomatrix subunit:Component of multiple ECS (ElonginThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role

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Description

subunit:Component of multiple ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes formed of CUL5

This protease degrades soluble and insoluble elastin

Activated by intracellular alkalinization

Actin proteins are major components of the eukaryotic cytoskeleton

Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE)

PAK gamma(Phospho Ser197) Polyclonal Antibody, 20ul Biomatrix subunit:Component of multiple ECS (ElonginThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role

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