PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4

The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks

is required for the apoptosis mediated by this protein

Also exhibits low-fidelity DNA synthesis

cofactor:Binds 1 Fe(3+) ion per subunit

PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies Alternatively spliced transcript variants encodingThis gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene