Human 5-Hydroxytryptamine Receptor 3A, HTR3A ELISA Kit, 96T CellSafe™ PubMed: 26165940)

PubMed: 26165940)

The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells

only GABBR1 seems to bind agonists

Alternatively spliced transcript variants encoding multiple isoforms have been observed

The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells

Human 5-Hydroxytryptamine Receptor 3A, HTR3A ELISA Kit, 96T CellSafe™ PubMed: 26165940)This is one of the several different receptors for 5 hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand gated ion Channel, which when activated causes fast, depolarizing responses in neurons. It is a cation specific, but otherwise relatively nonselective, ion Channel.