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ZO-2 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation This gene is physically linked

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ZO-2 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation This gene is physically linkedTJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in TJP2 have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal

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Description

This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13

dissociation of the TFEB/14-3-3 complex

The encoded protein is involved in platelet activation and controls the expression of interleukin-2

Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains

The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds

ZO-2 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation This gene is physically linkedTJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in TJP2 have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal

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