Shc Polyclonal Antibody, 20ul[BT-AP08290] Centrifuges Cholinergic receptor nicotinic alpha 5

Cholinergic receptor nicotinic alpha 5 subunit encoded by CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses

See also the muscle (PFKM

The p53 binding proteins 53BP1 and 53BP2 (Bbp) bind to the central DNA-binding domain of wild type p53

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus

Shc Polyclonal Antibody, 20ul[BT-AP08290] Centrifuges Cholinergic receptor nicotinic alpha 5SHC1 encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike the