Btk Polyclonal Antibody, 100ul[BT-AP01005] Insect Expression This gene encodes an alpha

This gene encodes an alpha 3 subunit

Mutations in this gene result in multiple epiphyseal dysplasia

which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy

Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches

possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome

Btk Polyclonal Antibody, 100ul[BT-AP01005] Insect Expression This gene encodes an alphaThe protein (Bruton tyrosine kinase) encoded by BTK plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.