CD56 Polyclonal Antibody, 100ul[BT-AP01761] Site-directed Mutagenesis and is overexpressed in the

and is overexpressed in the brain of Down syndrome fetuses

tissue specificity:Expressed in epithelial tumor cell lines of colonic

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

Two alternatively spliced transcript variants are expressed by the gene

thalamus and cerebral cortex

CD56 Polyclonal Antibody, 100ul[BT-AP01761] Site-directed Mutagenesis and is overexpressed in theThe checkpoint kinase 1 encoded by CHEK1 belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required