MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System which contain N-terminus EF-hand domains
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MARCH1 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System which contain N-terminus EF-hand domainsMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the
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