MARCH4 Polyclonal Antibody, 50ul Custom Peptide Synthesis which are extracellular signaling molecules

which are extracellular signaling molecules that play a role in embryonic development

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This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation

and therapy

Alternatively spliced transcript variants have been described| but their biological validity has not been determined

MARCH4 Polyclonal Antibody, 50ul Custom Peptide Synthesis which are extracellular signaling moleculesMARCH4 is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment.