PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody, 50ul Pipette Controller Deletion of this gene or

Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies

and cell polarization

A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified| but it is thought to be non-coding

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain

NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines| oxidant-free radicals| ultraviolet irradiation| and bacterial or viral products

PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody, 50ul Pipette Controller Deletion of this gene orThe protein encoded by this gene catalyzes the formation of inositol 1 4 5 trisphosphate and diacylglycerol from phosphatidylinositol 4 5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example when activated by SRC the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi where it