IGFL1 Polyclonal Antibody, 50ul Biochemical Reagents The human alanyl-tRNA synthetase (AARS)

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases| of the class II enzymes

which suggests a role of this gene in neuronal and lymphocyte apoptosis

The encoded protein plays a role in the inducible expression of cytokine genes in T cells

Multiple transcript variants encoding different isoforms have been found for STK3

Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain

IGFL1 Polyclonal Antibody, 50ul Biochemical Reagents The human alanyl-tRNA synthetase (AARS)The protein encoded by this gene is a member of the insulin like growth factor family of signaling molecules. The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide. The mature peptide binds to a receptor which in mouse was found on the cell surface of T cells. Increased expression of this gene may be linked to psoriasis.