SVIL Polyclonal Antibody, 50ul Funnels The protein encoded by CDC27

The protein encoded by CDC27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27

The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site| and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton| possibly by direct association with actin or spectrin

as well as multiple transcription activators

The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family| and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains

and endogenous substrates with ester

SVIL Polyclonal Antibody, 50ul Funnels The protein encoded by CDC27This gene encodes a bipartite protein with distinct amino and carboxy terminal domains. The amino terminus contains nuclear localization signals and the carboxy terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin binding proteins, which cap, nucleate, and or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role