Nibrin(Phospho Ser278) Polyclonal Antibody, 100ul Plasmid Preparation Lysine methylation occurs in three

Lysine methylation occurs in three distinct states

is retained in cytoplasm by YWHAZ

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

Pseudogenes corresponding to this gene are found on chromosomes 3p

Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling

Nibrin(Phospho Ser278) Polyclonal Antibody, 100ul Plasmid Preparation Lysine methylation occurs in threeMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint