SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette This gene autoregulates its expression

This gene autoregulates its expression by control of splicing of its first two introns

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and modulation of cell growth

Mutations in this gene may contribute to sterol accumulation and atheroschlerosis| and have been observed in patients with sitosterolemia

The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily

SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette This gene autoregulates its expressionSPZ1 (spermatogenic leucine zipper 1) encodes a bHLH zip transcription factor which functions in the mitogen activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, SPZ1 may serve as a target for Ras induced tumor treatments.