LIR-1 Polyclonal Antibody, 100ul Thermo Mix and may be involved in

and may be involved in inflammation and immune regulation

and functions as a mediator of the anti-apoptotic signals from TNF receptors

The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors

Binds to the DEATH domain of p75NTR/NGFR

In several variants

LIR-1 Polyclonal Antibody, 100ul Thermo Mix and may be involved inLILRB1 is a member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B1 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine based inhibitory motifs (ITIMs). The receptor is expressed on immune cells