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Raf-1(Phospho Ser296) Polyclonal Antibody, 20ul sgRNA customized design This gene is part of

SKU: 16130870060

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Raf-1(Phospho Ser296) Polyclonal Antibody, 20ul sgRNA customized design This gene is part ofThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

This gene is part of a cluster of cytochrome P450 genes on chromosome 19

and further to the allylic epoxide 5(S)-trans-7

the powerful enzyme with 20 Units/μL activity in a compact 1 mL package

Several transcript variants encoding different isoforms have been found for AMPD2

Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains

Raf-1(Phospho Ser296) Polyclonal Antibody, 20ul sgRNA customized design This gene is part ofThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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