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JAK2 Polyclonal Antibody, 50ul[BT-AP04687] Diagnostic Probes & Oligos Cytochrome P450 2C8/9/18/19 localizes to

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JAK2 Polyclonal Antibody, 50ul[BT-AP04687] Diagnostic Probes & Oligos Cytochrome P450 2C8/9/18/19 localizes toJAK2 product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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Description

Cytochrome P450 2C8/9/18/19 localizes to the endoplasmic reticulum but its specific substrate has not yet been determined

the protein was only detected in CD34+ progenitor cells present in blood and in CD31+ endothelial cells surrounding the blood vessels

|PTM:The level of phosphorylation appears to be regulated during the cell cycle

Mutations in this gene have been associated with disorders related to dopaminergic dysfunction

contains a GTP-binding motif

JAK2 Polyclonal Antibody, 50ul[BT-AP04687] Diagnostic Probes & Oligos Cytochrome P450 2C8/9/18/19 localizes toJAK2 product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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