Flt-3(Phospho Tyr842) Polyclonal Antibody, 50ul Immunoassays |Contains 1 Arf-GAP domain
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Flt-3(Phospho Tyr842) Polyclonal Antibody, 50ul Immunoassays |Contains 1 Arf-GAP domainThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,
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