TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Transcriptional adapter 2-alpha encoded by

Transcriptional adapter 2-alpha encoded by TADA2A is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex

Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site

Variable expression of RPS5 in colorectal cancers compared to adjacent normal tissues has been observed

See USP1 (MIM 603478) for background information

this protein induces the growth and differentiation of epithelial

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Transcriptional adapter 2-alpha encoded byCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only