AIF1 Polyclonal Antibody, 100ul Site-directed Mutagenesis The gene is located within

The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24

Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors

Several transcript variants encoding different isoforms have been found for CLIP1

This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems

This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis

AIF1 Polyclonal Antibody, 100ul Site-directed Mutagenesis The gene is located withinThis gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full length and coding nature of some of these variants is not certain.