Pim-1 Polyclonal Antibody, 100ul ADME Its depletion enhances the cytotoxic
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Pim-1 Polyclonal Antibody, 100ul ADME Its depletion enhances the cytotoxicThe protein encoded by PIM1 (Pim 1 proto oncogene, serine threonine kinase) belongs to the Ser Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both
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