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MSK1 Polyclonal Antibody, 50ul[BT-AP05625] Pathway and Network Analysis Alternative splicing and alternative promoter

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MSK1 Polyclonal Antibody, 50ul[BT-AP05625] Pathway and Network Analysis Alternative splicing and alternative promoterRPS6KA5 (Ribosomal Protein S6 Kinase A5) is a Protein Coding gene. Among its related pathways are cGMP PKG signaling pathway and Bladder cancer. GO annotations related to this gene include transferase activity, transferring phosphorus containing groups and protein tyrosine kinase activity. An important paralog of this gene is AKT1.

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Description

Alternative splicing and alternative promoter usage results in multiple transcript variants

depending on stage of neuronal maturation and neuron type

The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma

thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm

Mutations in CEP290 have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer

MSK1 Polyclonal Antibody, 50ul[BT-AP05625] Pathway and Network Analysis Alternative splicing and alternative promoterRPS6KA5 (Ribosomal Protein S6 Kinase A5) is a Protein Coding gene. Among its related pathways are cGMP PKG signaling pathway and Bladder cancer. GO annotations related to this gene include transferase activity, transferring phosphorus containing groups and protein tyrosine kinase activity. An important paralog of this gene is AKT1.

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