PAR14 Polyclonal Antibody, 100ul Measuring Instruments DNA reparation and mRNA packaging

DNA reparation and mRNA packaging

Ser-376 and Ser-212 are autophosphorylated by the C-terminal kinase domain

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The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles

since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain

PAR14 Polyclonal Antibody, 100ul Measuring Instruments DNA reparation and mRNA packagingThis gene encodes a member of the poly(ADP ribose) polymerase (PARP) protein family. The encoded anti apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types.