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AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Translocations involving this gene play

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AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Translocations involving this gene playJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Description

Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma

suggesting a possible role for CTSV in tumor processes

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins

ABC proteins transport various molecules across extra-and intra-cellular membranes

AP-1 (Acetyl Lys271) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging Translocations involving this gene playJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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