Histone H4 (Di Methyl Lys21) Rabbit Polyclonal Antibody, 50ul Gene Editing They also have isopeptidase activity

They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates

Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor

A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein

May be a marker of CD4(+) CD56(+) leukemic tumor cells

Negative regulator of host innate immune defense against viruses

Histone H4 (Di Methyl Lys21) Rabbit Polyclonal Antibody, 50ul Gene Editing They also have isopeptidase activityCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone code and nucleosome remodeling. PTM: Acetylation at