PDE4B Rabbit Polyclonal Antibody, 100ul Immune Repertoire Sequencing A pseudogene of this gene

A pseudogene of this gene has been identified on chromosome 6

thereby influencing several biological processes

and age-related macular degeneration type 3 (ARMD3)

Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression

Defects in ITGA7 are associated with congenital myopathy

PDE4B Rabbit Polyclonal Antibody, 100ul Immune Repertoire Sequencing A pseudogene of this geneThis gene is a member of the type IV cyclic AMP (cAMP) specific cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding