IRAK-4 Monoclonal Antibody, 50ul Inoculating Loops/Needles Members of the ABC1 subfamily

Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes

Alternatively spliced transcript variants encoding multiple isoforms have been observed for TCF3

perfect for ambient shipping and room temperature storage

Polymorphisms in this gene may be associated with type 2 diabetes

may be associated with split-hand/split-foot malformation

IRAK-4 Monoclonal Antibody, 50ul Inoculating Loops/Needles Members of the ABC1 subfamilyThis gene encodes a kinase that activates NF kappaB in both the Toll like receptor (TLR) and T cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.