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TM217 Rabbit Polyclonal Antibody, 20ul Cryopreservation PABPC5 is located in a

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TM217 Rabbit Polyclonal Antibody, 20ul Cryopreservation PABPC5 is located in a

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Description

PABPC5 is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC)

CA VA is localized in the mitochondria and expressed primarily in the liver

It also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner

Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH)

TM217 Rabbit Polyclonal Antibody, 20ul Cryopreservation PABPC5 is located in a

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