T2R42 Polyclonal Antibody, 100ul Supplements Mutations in PSAP have been

Mutations in PSAP have been associated with Gaucher disease and metachromatic leukodystrophy

It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events

By itself| the protein has 3' to 5' exonuclease activity and endonuclease activity

resulting in phosphorylation of type I receptors by type II receptors

Contains 2 Macro domains

T2R42 Polyclonal Antibody, 100ul Supplements Mutations in PSAP have beenReceptor that may play a role in the perception of bitterness and is gustducin linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC beta 2 activation and lead to the gating of TRPM5.,miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,Belongs