NPC1 Rabbit Polyclonal Antibody, 50ul Transporters May play a role in

May play a role in hypermutation of immunogobulin genes

The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues

This gene encodes a member of the RAS-like small GTP-binding protein superfamily

An important paralog of this gene is TNFAIP8L2

involved in leukocyte transmigration

NPC1 Rabbit Polyclonal Antibody, 50ul Transporters May play a role inThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments