Raf-1 Polyclonal Antibody, 20ul[BT-AP13534] Cell Labeling & Imaging Apoptosis antagonizing transcription factor encoded

Apoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12/DLK

DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain

Phosphorylation of Ser-51 does not affect DNA repair

The ligands of these receptors are members of the TGF-beta superfamily

lacking the N-terminal hydrophobic region but retaining the same activity

Raf-1 Polyclonal Antibody, 20ul[BT-AP13534] Cell Labeling & Imaging Apoptosis antagonizing transcription factor encodedThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.