Syntenin-2 Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis Polymorphisms in CA8 are associated

Polymorphisms in CA8 are associated with osteoporosis

and being expressed in vascular endothelium cells and binding to L-selectin

Expression of this gene is up-regulated in some types of cancer

early growth response factors (Egrs) and fibroblast growth receptors (FGFRs)

Mutations in this gene cause hyperlipoproteinemia type IB

Syntenin-2 Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis Polymorphisms in CA8 are associatedThe protein encoded by this gene was initially identified as a molecule linking syndecan mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic C terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal membrane organization cell adhesion protein trafficking and the activation of transcription factors. The protein is primarily localized to