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Beclin-1 Polyclonal Antibody, 50ul[BT-AP00883] Measuring Instruments This gene encodes the small

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Beclin-1 Polyclonal Antibody, 50ul[BT-AP00883] Measuring Instruments This gene encodes the smallBECN1 (beclin 1) encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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Description

This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers

May be involved in neuronal migration

There are pseudogenes for EIF3J on chromosomes 1

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes

An important paralog of this gene is ZSCAN16

Beclin-1 Polyclonal Antibody, 50ul[BT-AP00883] Measuring Instruments This gene encodes the smallBECN1 (beclin 1) encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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