HNK-1ST Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in this gene are

Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D| and expression of this gene may be a prognostic indicator for several types of cancer

Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections

The protein encoded by this gene is a member of the Mastermind-like family of proteins

enhancing beta-catenin degradation

Two transcript variants encoding the same protein have been identified

HNK-1ST Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in this gene areCarbohydrate sulfotransferase 10 encoded by CHST10 transfers sulfate to the C 3 hydroxyl of terminal glucuronic acid of protein and lipid linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer 1 (HNK 1) glycan; HNK 1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.