ERCC4 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging An important paralog of this

An important paralog of this gene is ANKRD18A

recruited to tight junctions (TJ) during the maturation of the TJ complexes

and inhibits bone morphogenetic protein (BMP) function

Pseudogenes corresponding to this gene are found on chromosomes 2p

The product of this reaction is necessary for DNA synthesis

ERCC4 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging An important paralog of thisERCC excision repair 4, endonuclease catalytic subunit encoded by ERCC4 forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP F), or xeroderma pigmentosum VI (XP6).