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Raf-1 Polyclonal Antibody, 50ul[BT-AP07627] Pipette Controller This gene belongs to the

SKU: 10856161742

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Raf-1 Polyclonal Antibody, 50ul[BT-AP07627] Pipette Controller This gene belongs to theRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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Description

This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes

These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter

This gene is overexpressed in colon tumors

It functions through either direct interaction with components of the antigen receptor complexes

DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins

Raf-1 Polyclonal Antibody, 50ul[BT-AP07627] Pipette Controller This gene belongs to theRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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